Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy

Abstract This study investigated the effects of indirubin on autophagy and apoptosis in cervical cancer models, with a focus on elucidating the underlying molecular mechanisms. A xenograft tumor model in BALB/c-Nude mice and in vitro experiments using HeLa cell lines were employed. Indirubin treatme...

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Autors principals:	Xiuchao Xie, Chang Liu, Xiaoling Liu, Lin Hou, Ya Zhang, Lin Huang, Weidong Peng, Yu Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-01-01
Col·lecció:	Scientific Reports
Matèries:	Indirubin Cervical cancer HeLa PI3K/AKT MAPK
Accés en línia:	https://doi.org/10.1038/s41598-026-35382-z
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