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Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens

ABSTRACT: Follicular atresia in chickens reduces the number of follicles that can further develop, leading to decrease egg laying. Endoplasmic reticulum stress (ERS) can initiate a unique pathway inducing the apoptosis of follicular granulosa cells, thus reducing egg laying. Melatonin (MEL) is invol...

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Principais autores: Er-ying Hao, Xue-lu Liu, Xiang-yu Chen, Han Xue, Bo-fei Su, Yi-fan Chen, De-he Wang, Lei Shi, Kang Bai, Fei Hou, Jian-ku Hou, Hui-ling Bao, Hui Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-06-01
coleção:Poultry Science
Assuntos:
MEL
ERS
mTOR
granulosa cell
chicken
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0032579124002359
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