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Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to trac...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Justin Judd, Fang Wei, Peter Q Nguyen, Lawrence J Tartaglia, Mavis Agbandje-McKenna, Jonathan J Silberg, Junghae Suh
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2012-01-01
Rangatū:Molecular Therapy: Nucleic Acids
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2162253116301111
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