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Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to trac...

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Detaylı Bibliyografya
Asıl Yazarlar: Justin Judd, Fang Wei, Peter Q Nguyen, Lawrence J Tartaglia, Mavis Agbandje-McKenna, Jonathan J Silberg, Junghae Suh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2012-01-01
Seri Bilgileri:Molecular Therapy: Nucleic Acids
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2162253116301111
Etiketler: Etiketle
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