TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells

Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and the development of chronic kidney disease (CKD), which can be mediated by aberrant innate immune activation, mitochondrial pathology, and accumulation of senescent tubular epithelial cells (...

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Detalhes bibliográficos

Principais autores:	Alessandra Tammaro, Angelique M. L. Scantlebery, Elena Rampanelli, Cristiana Borrelli, Nike Claessen, Loes M. Butter, Alessandra Soriani, Marco Colonna, Jaklien C. Leemans, Mark C. Dessing, Sandrine Florquin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-07-01
coleção:	Frontiers in Immunology
Assuntos:	maladaptive repair mitochondrial metabolism tubular cell senescence epithelial innate immunity renal repair ischemia/reperfusion injury
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01469/full
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