NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy

Background: Chronic kidney disease often leads to kidney dysfunction due to renal fibrosis, regardless of the initial cause of kidney damage. Macrophages are crucial players in the progression of renal fibrosis as they stimulate inflammation, activate fibroblasts, and contribute to extracellular mat...

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Detalhes bibliográficos

Principais autores:	Ye Liu, Lotte Kors, Loes M. Butter, Geurt Stokman, Nike Claessen, Coert J. Zuurbier, Stephen E. Girardin, Jaklien C. Leemans, Sandrine Florquin, Alessandra Tammaro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-12-01
Colecção:	Cells
Assuntos:	NLRX1 macrophage polarization OXPHOS renal fibrosis
Acesso em linha:	https://www.mdpi.com/2073-4409/13/1/23
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