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Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea

Study objectives: Chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA), induces accelerated atherogenesis as well as aorta vascular remodeling. Although the cyclooxygenase (COX) pathway has been proposed to contribute to the cardiovascular consequences of OSA, the...

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Principais autores: Monique C. Suarez-Giron, Anabel Castro-Grattoni, Marta Torres, Ramon Farré, Ferran Barbé, Manuel Sánchez-de-la-Torre, David Gozal, Cesar Picado, Josep M. Montserrat, Isaac Almendros
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-05-01
Serier:Frontiers in Physiology
Fag:
intermittent hypoxia
sleep apnea
obstructive
acetilsalicilic acid
cardiovascular diseases
aortic remodeling
Online adgang:https://www.frontiersin.org/article/10.3389/fphys.2018.00600/full
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