Computational Study on Selective PDE9 Inhibitors on PDE9-Mg/Mg, PDE9-Zn/Mg, and PDE9-Zn/Zn Systems

PDE9 inhibitors have been studied to validate their potential to treat diabetes, neurodegenerative disorders, cardiovascular diseases, and erectile dysfunction. In this report, we have selected highly potent previously reported selective PDE9 inhibitors BAY73-6691R, BAY73-6691S, 28r, 28s, 3r, 3s, PF...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dakshinamurthy Sivakumar, Sathishkumar Mudedla, Seonghun Jang, Hyunjun Kim, Hyunjin Park, Yonwon Choi, Joongyo Oh, Sangwook Wu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-05-01
Цуврал:	Biomolecules
Нөхцлүүд:	selective inhibitors PDE9 molecular dynamics metal complexes BAY73-6691
Онлайн хандалт:	https://www.mdpi.com/2218-273X/11/5/709
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!