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Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

Embryonic patterning in vertebrates is dependent upon the balance of inductive signals and their specific antagonists. We show that Noggin, which encodes a bone morphogenetic protein (BMP) antagonist expressed in the node, notochord, and dorsal somite, is required for normal mouse development. Altho...

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Detalhes bibliográficos
Main Authors: McMahon, Jill A., Takada, Shinji, Zimmerman, Lyle B., Fan, Chen-Ming, Harland, Richard M., McMahon, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316831/
https://ncbi.nlm.nih.gov/pubmed/9585504
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