Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases

The Rho associated coiled-coil containing protein kinase (ROCK1 and ROCK2) and myotonic dystrophy-related Cdc-42 binding kinases (MRCKα and MRCKβ) are critical regulators of cell proliferation and cell plasticity, a process intimately involved in cancer cell migration and invasion. Previously, we re...

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Hauptverfasser:	Vijay Pralhad Kale, Jeremy A. Hengst, Arati K. Sharma, Upendarrao Golla, Sinisa Dovat, Shantu G. Amin, Jong K. Yun, Dhimant H. Desai
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-07-01
Schriftenreihe:	Pharmaceuticals
Schlagworte:	ROCK MRCK multi-kinase inhibitor cancer invasion metastasis
Online-Zugang:	https://www.mdpi.com/1424-8247/16/8/1060
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