Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

<p>Abstract</p> <p>Background</p> <p>Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryonic or perinatal lethality and the compensatory regulat...

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Hlavní autoři:	Sablitzky Fred, Niclou Simone P, Levelt Christiaan, Zhang Jing, Hermens Wim TJMC, Eggers Ruben, Chakravarthy Sridhara, Ahmed Bushra Y, Anderson Patrick N, Lieberman AR, Verhaagen Joost
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2004-01-01
Edice:	BMC Neuroscience
On-line přístup:	http://www.biomedcentral.com/1471-2202/5/4
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