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Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma

Increased cancer incidence occurs with the emergence of immunosenescence, highlighting the indispensability of the immune system in preventing cancer and its dysregulation with aging. Tumor-associated macrophages (TAMs) are often present in high numbers and are associated with poor clinical outcomes...

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Autors principals: Lelinh Duong, Fiona J. Pixley, Delia J. Nelson, Connie Jackaman
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-04-01
Col·lecció:Frontiers in Aging
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fragi.2022.848925/full
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