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Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma

Increased cancer incidence occurs with the emergence of immunosenescence, highlighting the indispensability of the immune system in preventing cancer and its dysregulation with aging. Tumor-associated macrophages (TAMs) are often present in high numbers and are associated with poor clinical outcomes...

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Principais autores: Lelinh Duong, Fiona J. Pixley, Delia J. Nelson, Connie Jackaman
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2022-04-01
丛编:Frontiers in Aging
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在线阅读:https://www.frontiersin.org/articles/10.3389/fragi.2022.848925/full
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