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Protein Tyrosine Phosphatase φ Regulates Paxillin Tyrosine Phosphorylation and Mediates Colony-Stimulating Factor 1-Induced Morphological Changes in Macrophages

Removal of colony-stimulating factor 1 (CSF-1) causes macrophages to round up and to increase their expression of protein tyrosine phosphatase φ (PTPφ). This is accompanied by the disruption of focal complexes and the formation of ruffles. Here we have overexpressed wild-type (WT) PTPφ and a phospha...

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Detalhes bibliográficos
Main Authors: Pixley, Fiona J., Lee, Pierre S. W., Condeelis, John S., Stanley, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86738/
https://ncbi.nlm.nih.gov/pubmed/11238916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1795-1809.2001
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