Transcription factor network dynamics during the commitment to oncogene-induced senescence
Aberrant oncogenic signaling causes cells to transition into oncogene-induced senescence (OIS) to limit uncontrolled proliferation. Despite being a potent tumor suppressor mechanism, OIS is an unstable cell state susceptible to reprogramming that can promote tumorigenesis. Therefore, elucidating the...
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| Автори: | , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2024-07-01
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| Серія: | Frontiers in Epigenetics and Epigenomics |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/freae.2024.1423454/full |
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