NR4A1 transcriptionally regulates the differentiation of stem-like CD8+ T cells in the tumor microenvironment

Summary: CD8+ T cells are rendered exhausted in tumor and chronic infection. Among heterogeneous exhausted T cells, a subpopulation of progenitor-like (Tpex) cells have been found important for long-term tumor or pathogen control and are also the main responders in immunotherapy. Using an RFP report...

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Detalhes bibliográficos

Principais autores:	Jing Hao, Ruifeng Li, Xiaohong Zhao, Xinwei Liu, Xiang Chen, Tian Xie, Xiaoli Li, Chenjun Yao, Qinli Sun, Kun Wei, Mengting Gou, Xinxin Chi, Wei Xu, Ling Ni, Chen Dong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
Colecção:	Cell Reports
Assuntos:	CP: Immunology CP: Cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124724006296
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