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Transcription factor network dynamics during the commitment to oncogene-induced senescence

Aberrant oncogenic signaling causes cells to transition into oncogene-induced senescence (OIS) to limit uncontrolled proliferation. Despite being a potent tumor suppressor mechanism, OIS is an unstable cell state susceptible to reprogramming that can promote tumorigenesis. Therefore, elucidating the...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Themistoklis Vasilopoulos, Ricardo Iván Martínez-Zamudio
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2024-07-01
Rangatū:Frontiers in Epigenetics and Epigenomics
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/freae.2024.1423454/full
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