Synthesis of Microwave Functionalized, Nanostructured Polylactic Co-Glycolic Acid (<i>nf</i>PLGA) for Incorporation into Hydrophobic Dexamethasone to Enhance Dissolution

The low solubility and slow dissolution of hydrophobic drugs is a major challenge for the pharmaceutical industry. In this paper, we present the synthesis of surface-functionalized poly(lactic-co-glycolic acid) (PLGA) nanoparticles for incorporation into corticosteroid dexamethasone to improve its i...

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Автори:	Mohammad Saiful Islam, Somenath Mitra
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2023-03-01
Серія:	Nanomaterials
Предмети:	hydrophobic drug FDA polymer microwave functionalization dexamethasone in vitro dissolution absorption bioavailability
Онлайн доступ:	https://www.mdpi.com/2079-4991/13/5/943
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