Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(lactic-<i>co</i>-glycolic acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity

For the treatment of sinus surgery-induced osteitis in chronic rhinosinusitis (CRS), oral or intranasal administration of corticoids is generally used, although it has critical limitations and unavoidable side effects. To overcome these limitations, we designed dexamethasone (Dex)-loaded poly(lactic...

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Principais autores:	Seung-No Hong, Minjae Kim, Jin-A Park, Minji Kang, Hyunkyung Cha, Sohyun Park, Joon Kon Kim, Jinyoung Pac, Yuju Seo, Sungwhan Kim, Minju Kim, Dae Woo Kim, Yan Lee
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-02-01
Series:	Pharmaceutics
Assuntos:	chronic rhinosinusitis osteitis dexamethasone sinonasal cavity calcium binding poly(lactic-<i>co</i>-glycolic acid) (PLGA)
Acceso en liña:	https://www.mdpi.com/1999-4923/14/3/546
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