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Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(lactic-<i>co</i>-glycolic acid) (PLGA) Microparticles with Strong Calcium-Binding Affinity

For the treatment of sinus surgery-induced osteitis in chronic rhinosinusitis (CRS), oral or intranasal administration of corticoids is generally used, although it has critical limitations and unavoidable side effects. To overcome these limitations, we designed dexamethasone (Dex)-loaded poly(lactic...

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Principais autores: Seung-No Hong, Minjae Kim, Jin-A Park, Minji Kang, Hyunkyung Cha, Sohyun Park, Joon Kon Kim, Jinyoung Pac, Yuju Seo, Sungwhan Kim, Minju Kim, Dae Woo Kim, Yan Lee
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Pharmaceutics
Fag:
chronic rhinosinusitis
osteitis
dexamethasone
sinonasal cavity
calcium binding
poly(lactic-<i>co</i>-glycolic acid) (PLGA)
Online adgang:https://www.mdpi.com/1999-4923/14/3/546
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