Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments

Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools to model disease and assess the toxicity of pharmaceutical medications. A common limitation of cell lineages derived from iPSCs is a blunted phenotype compared with fully developed, endogenous cells. We exami...

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Hlavní autoři:	Bo Wang, Adam E. Jakus, Pedro M. Baptista, Shay Soker, Alejandro Soto-Gutierrez, Michael M. Abecassis, Ramille N. Shah, Jason A. Wertheim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2016-09-01
Edice:	Stem Cells Translational Medicine
Témata:	Liver Stem cell‐microenvironment interactions Stem/progenitor cell Tissue regeneration Induced pluripotent stem cells
On-line přístup:	https://doi.org/10.5966/sctm.2015-0235
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