Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments

Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools to model disease and assess the toxicity of pharmaceutical medications. A common limitation of cell lineages derived from iPSCs is a blunted phenotype compared with fully developed, endogenous cells. We exami...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Bo Wang, Adam E. Jakus, Pedro M. Baptista, Shay Soker, Alejandro Soto-Gutierrez, Michael M. Abecassis, Ramille N. Shah, Jason A. Wertheim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2016-09-01
coleção:	Stem Cells Translational Medicine
Assuntos:	Liver Stem cell‐microenvironment interactions Stem/progenitor cell Tissue regeneration Induced pluripotent stem cells
Acesso em linha:	https://doi.org/10.5966/sctm.2015-0235
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!