Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments

Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools to model disease and assess the toxicity of pharmaceutical medications. A common limitation of cell lineages derived from iPSCs is a blunted phenotype compared with fully developed, endogenous cells. We exami...

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Главные авторы:	Bo Wang, Adam E. Jakus, Pedro M. Baptista, Shay Soker, Alejandro Soto-Gutierrez, Michael M. Abecassis, Ramille N. Shah, Jason A. Wertheim
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 2016-09-01
Серии:	Stem Cells Translational Medicine
Предметы:	Liver Stem cell‐microenvironment interactions Stem/progenitor cell Tissue regeneration Induced pluripotent stem cells
Online-ссылка:	https://doi.org/10.5966/sctm.2015-0235
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