Prediction of co-receptor usage of HIV-1 from genotype.
Human Immunodeficiency Virus 1 uses for entry into host cells a receptor (CD4) and one of two co-receptors (CCR5 or CXCR4). Recently, a new class of antiretroviral drugs has entered clinical practice that specifically bind to the co-receptor CCR5, and thus inhibit virus entry. Accurate prediction of...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2010-04-01
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| Seria: | PLoS Computational Biology |
| Dostęp online: | http://europepmc.org/articles/PMC2855328?pdf=render |
| Etykiety: |
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