Prediction of co-receptor usage of HIV-1 from genotype.
Human Immunodeficiency Virus 1 uses for entry into host cells a receptor (CD4) and one of two co-receptors (CCR5 or CXCR4). Recently, a new class of antiretroviral drugs has entered clinical practice that specifically bind to the co-receptor CCR5, and thus inhibit virus entry. Accurate prediction of...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2010-04-01
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| Edice: | PLoS Computational Biology |
| On-line přístup: | http://europepmc.org/articles/PMC2855328?pdf=render |
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