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Prediction of co-receptor usage of HIV-1 from genotype.

Human Immunodeficiency Virus 1 uses for entry into host cells a receptor (CD4) and one of two co-receptors (CCR5 or CXCR4). Recently, a new class of antiretroviral drugs has entered clinical practice that specifically bind to the co-receptor CCR5, and thus inhibit virus entry. Accurate prediction of...

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Váldodahkkit: J Nikolaj Dybowski, Dominik Heider, Daniel Hoffmann
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2010-04-01
Ráidu:PLoS Computational Biology
Liŋkkat:http://europepmc.org/articles/PMC2855328?pdf=render
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