Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells

Abstract Background Nucleocytoplasmic transport is a tightly regulated process carried out by specific transport machinery, the defects of which may lead to a number of diseases including cancer. Karyopherin alpha 7 (KPNA7), the newest member of the karyopherin alpha nuclear importer family, is expr...

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Principais autores:	Elisa M. Vuorinen, Nina K. Rajala, Teemu O. Ihalainen, Anne Kallioniemi
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2018-03-01
Series:	BMC Cancer
Assuntos:	KPNA7 Importin alpha 8 Nuclear transfer Nuclear morphology Cell proliferation Mitosis
Acceso en liña:	http://link.springer.com/article/10.1186/s12885-018-4261-5
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