Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene. The myogenesis process is defective in DM1, which is closely associated with progressive muscle weakness and wasting. Despite many proposed exp...

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Bibliografski detalji

Glavni autori:	Xiaopeng Shen, Zhongxian Liu, Chunguang Wang, Feng Xu, Jingyi Zhang, Meng Li, Yang Lei, Ao Wang, Chao Bi, Guoping Zhu
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-08-01
Serija:	Frontiers in Cell and Developmental Biology
Teme:	Postn myotonic dystrophy type 1 microenvironment myoblast myogenesis
Online pristup:	https://www.frontiersin.org/articles/10.3389/fcell.2021.710112/full
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