Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene. The myogenesis process is defective in DM1, which is closely associated with progressive muscle weakness and wasting. Despite many proposed exp...

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Prif Awduron:	Xiaopeng Shen, Zhongxian Liu, Chunguang Wang, Feng Xu, Jingyi Zhang, Meng Li, Yang Lei, Ao Wang, Chao Bi, Guoping Zhu
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2021-08-01
Cyfres:	Frontiers in Cell and Developmental Biology
Pynciau:	Postn myotonic dystrophy type 1 microenvironment myoblast myogenesis
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fcell.2021.710112/full
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