Mincle receptor agonist UM-1098 and TLR4 agonist INI-2002 combination adjuvant enhances Th1 responses and provides protection against Mycobacterium tuberculosis challenge in mice
Adjuvants targeting pattern recognition receptors (PRRs) can selectively skew the immune responses towards a Th1, Th2 or Th17 phenotype following vaccination. However, for diseases such as tuberculosis (TB), mixed Th cell responses, especially Th1/Th17 are considered important for protection. Hence,...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2025-10-01
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| Seri Bilgileri: | Vaccine: X |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2590136225000932 |
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