Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons
<p>Abstract</p> <p>Background</p> <p>Glutathione (GSH) plays an important role in neuronal oxidant defence. Depletion of cellular GSH is observed in neurodegenerative diseases and thereby contributes to the associated oxidative stress and Ca<sup>2+ </sup>dysregulation. Whether depletion of cellular...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2012-04-01
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| Col·lecció: | Molecular Brain |
| Matèries: | |
| Accés en línia: | http://www.molecularbrain.com/content/5/1/11 |
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