D-serine and serine racemase are associated with PSD-95 and glutamatergic synapse stability

D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine. It is crucial for synaptic plasticity and is implicated in schizophrenia. Our previous studies demonstrated specific loss of SR, D-serine-r...

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Autors principals:	Hong eLin, Ariel A. Jacobi, Stewart A. Anderson, David R. Lynch
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2016-02-01
Col·lecció:	Frontiers in Cellular Neuroscience
Matèries:	Astrocytes d-serine NMDA receptor cortical neurons postsynaptic PSD-95
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00034/full
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