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DNA methylation of the first exon is tightly linked to transcriptional silencing.

Tissue specific patterns of methylated cytosine residues vary with age, can be altered by environmental factors, and are often abnormal in human disease yet the cellular consequences of DNA methylation are incompletely understood. Although the bodies of highly expressed genes are often extensively m...

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Библиографические подробности
Главные авторы: Fabienne Brenet, Michelle Moh, Patricia Funk, Erika Feierstein, Agnes J Viale, Nicholas D Socci, Joseph M Scandura
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2011-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3022582?pdf=render
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