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Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat β-tropomyosin gene

In the rat β-tropomyosin (β-TM) gene, exons 6 and 7 are spliced alternatively in a mutually exclusive manner. Exon 6 is included in mRNA encoding nonmuscle TM-1, whereas exon 7 is used in mRNA encoding skeletal muscle β-TM. Previously, we demonstrated that a six nucleotide mutation at the 5′ end of...

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Detalhes bibliográficos
Main Authors: Chen, Charlie Degui, Kobayashi, Ryuji, Helfman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316507/
https://ncbi.nlm.nih.gov/pubmed/10072387
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