Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat β-tropomyosin gene

In the rat β-tropomyosin (β-TM) gene, exons 6 and 7 are spliced alternatively in a mutually exclusive manner. Exon 6 is included in mRNA encoding nonmuscle TM-1, whereas exon 7 is used in mRNA encoding skeletal muscle β-TM. Previously, we demonstrated that a six nucleotide mutation at the 5′ end of...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Chen, Charlie Degui, Kobayashi, Ryuji, Helfman, David M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10072387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.5.593
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