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Evaluation of a reference antibody panel for prediction of cytokine release in humanised mouse models in vivo

IntroductionA diverse range of innovative biological therapies is being developed to treat various human diseases. The safety assessment of these biologics is a critical factor determining clinical success. Enhanced humanised mouse models have the potential to revolutionise immunotoxicological profi...

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Bibliografische gegevens
Hoofdauteurs: Deepa Rajagopal, Ka Seng Ieong, Ryan Mate, Sandrine Vessillier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2026-03-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1736130/full
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