A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in Escherichia coli

Summary: The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer promise to identify compounds while providing strong...

Descripció completa

Dades bibliogràfiques

Autors principals:	Kenneth Rachwalski, Sean J. Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Adele Girgis-Gabardo, Megan Tu, Rodion Gordzevich, Rowan Ives, Amelia B.Y. Guo, Jarrod W. Johnson, Yiming Xu, Sharookh B. Kapadia, Jakob Magolan, Eric D. Brown
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-10-01
Col·lecció:	iScience
Matèries:	Microbiology Biotechnology Cell biology
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589004224021199
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!