A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in Escherichia coli

Summary: The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer promise to identify compounds while providing strong...

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Ngā kaituhi matua:	Kenneth Rachwalski, Sean J. Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Adele Girgis-Gabardo, Megan Tu, Rodion Gordzevich, Rowan Ives, Amelia B.Y. Guo, Jarrod W. Johnson, Yiming Xu, Sharookh B. Kapadia, Jakob Magolan, Eric D. Brown
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2024-10-01
Rangatū:	iScience
Ngā marau:	Microbiology Biotechnology Cell biology
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2589004224021199
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!