A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in Escherichia coli

Summary: The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer promise to identify compounds while providing strong...

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Bibliografische gegevens

Hoofdauteurs:	Kenneth Rachwalski, Sean J. Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Adele Girgis-Gabardo, Megan Tu, Rodion Gordzevich, Rowan Ives, Amelia B.Y. Guo, Jarrod W. Johnson, Yiming Xu, Sharookh B. Kapadia, Jakob Magolan, Eric D. Brown
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2024-10-01
Reeks:	iScience
Onderwerpen:	Microbiology Biotechnology Cell biology
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2589004224021199
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