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A host defense role for Fibrinogen by direct binding of Clostridium botulinum C2 toxin

Abstract In addition to fibrinogens canonical function in hemostasis, alternate roles in innate immunity have emerged. However, interactions with bacterial protein toxins, the main virulence factors of many medically relevant bacteria and causative agents of life-threatening diseases, have not been...

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Principais autores: Sophia Kistermann, Sebastian Heber, Stephan Fischer, Jannik Sichau, Christoph Q. Schmidt, Marco Mannes, Markus Huber-Lang, Holger Barth
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2026-05-01
Series:Cellular and Molecular Life Sciences
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Acceso en liña:https://doi.org/10.1007/s00018-026-06253-7
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