Alpha-1 antitrypsin inhibits Clostridium botulinum C2 toxin, Corynebacterium diphtheriae diphtheria toxin and B. anthracis fusion toxin

Abstract The bacterium Clostridium botulinum, well-known for producing botulinum neurotoxins, which cause the severe paralytic illness known as botulism, produces C2 toxin, a binary AB-toxin with ADP-ribosyltranferase activity. C2 toxin possesses two separate protein components, an enzymatically act...

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Үндсэн зохиолчид:	Stefanie Lietz, Lena-Marie Sokolowski, Holger Barth, Katharina Ernst
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2024-09-01
Цуврал:	Scientific Reports
Нөхцлүүд:	α1-Antitrypsin Toxin inhibitor Clostridium botulinum C2 toxin Diphtheria toxin Anthrax toxin Drug repurposing
Онлайн хандалт:	https://doi.org/10.1038/s41598-024-71706-7
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!