A host defense role for Fibrinogen by direct binding of Clostridium botulinum C2 toxin

Abstract In addition to fibrinogens canonical function in hemostasis, alternate roles in innate immunity have emerged. However, interactions with bacterial protein toxins, the main virulence factors of many medically relevant bacteria and causative agents of life-threatening diseases, have not been...

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Manylion Llyfryddiaeth

Prif Awduron:	Sophia Kistermann, Sebastian Heber, Stephan Fischer, Jannik Sichau, Christoph Q. Schmidt, Marco Mannes, Markus Huber-Lang, Holger Barth
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Springer 2026-05-01
Cyfres:	Cellular and Molecular Life Sciences
Pynciau:	Bacterial protein toxin Blood coagulation factor C2 toxin Clostridium botulinum Fibrinogen Toxin inhibitor
Mynediad Ar-lein:	https://doi.org/10.1007/s00018-026-06253-7
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