CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains

Abstract Background Genomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted gene domains has mostly been lacking. Here, we explo...

ver descrição completa

Detalhes bibliográficos

Principais autores:	David Llères, Benoît Moindrot, Rakesh Pathak, Vincent Piras, Mélody Matelot, Benoît Pignard, Alice Marchand, Mallory Poncelet, Aurélien Perrin, Virgile Tellier, Robert Feil, Daan Noordermeer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-12-01
coleção:	Genome Biology
Assuntos:	Genomic imprinting 3D genome organization Dlk1 Meg3 Igf2 CTCF
Acesso em linha:	https://doi.org/10.1186/s13059-019-1896-8
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!