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A complex regulatory landscape involved in the development of mammalian external genitals

Developmental genes are often controlled by large regulatory landscapes matching topologically associating domains (TADs). In various contexts, the associated chromatin backbone is modified by specific enhancer–enhancer and enhancer–promoter interactions. We used a TAD flanking the mouse HoxD cluste...

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Autori principali: Ana Rita Amândio, Lucille Lopez-Delisle, Christopher Chase Bolt, Bénédicte Mascrez, Denis Duboule
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2020-04-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/52962
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