Código QR

Tissue pharmacokinetics of antisense oligonucleotides

Pharmacokinetics (PK) of antisense oligonucleotides (ASOs) is characterized by rapid distribution from plasma to tissue and slow terminal plasma elimination driven by re-distribution from tissue. Quantitative understanding of tissue PK and RNA knockdown for various ASO chemistries, conjugations, and...

ver descrição completa

Na minha lista:
Principais autores: Erica Bäckström, Alessandro Bonetti, Per Johnsson, Stefan Öhlin, Anders Dahlén, Patrik Andersson, Shalini Andersson, Peter Gennemark
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-03-01
Colecção:Molecular Therapy: Nucleic Acids
Assuntos:
MT: oligonucleotides: therapies and applications
pharmacokinetics
antisense oligonucleotides
mouse
tissue
distribution
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2162253124000209
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados