A bactericidal tuberculosis drug regimen driven by inhibition of the terminal oxidases by pretomanid
Abstract Pretomanid is a unique anti-tuberculosis agent that inhibits both cell-wall synthesis and bioenergetics in Mycobacterium tuberculosis. While targeting the cell wall triggers a rapid bactericidal effect on replicating mycobacteria, the release of nitric oxide is linked to bactericidal potenc...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Nature
2026-02-01
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| Col·lecció: | EMBO Molecular Medicine |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1038/s44321-026-00378-9 |
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