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Cohesin promotes HSV-1 lytic transcription by facilitating the binding of RNA Pol II on viral genes

Abstract Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus. Cohesin, a major constituent of interphase and mitotic chromosomes comprised of SMC1, SMC3, and SCC1 (Mcd1/Rad21), SCC3...

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Autors principals: Xin Li, Yafen Yu, Fengchao Lang, Guijun Chen, Erlin Wang, Lihong Li, Zhuoran Li, Liping Yang, Xia Cao, Nigel W. Fraser, Jumin Zhou
Format: Artigo
Idioma:Inglês
Publicat: BMC 2021-01-01
Col·lecció:Virology Journal
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Accés en línia:https://doi.org/10.1186/s12985-021-01495-2
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