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Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Abstract Background Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG). Infected tree shrew differs from mouse and show characteristics similar to human infection. A detailed transcriptom...

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Автори: Erlin Wang, Yunshuang Ye, Ke Zhang, Jinlong Yang, Daohua Gong, Jianhua Zhang, Renjun Hong, Huan Zhang, Lihong Li, Guijun Chen, Liping Yang, Jianmei Liu, Hanyu Cao, Ting Du, Nigel W. Fraser, Le Cheng, Xia Cao, Jumin Zhou
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2020-07-01
Серія:Virology Journal
Предмети:
HSV-1
Tree shrew
RNAseq
Trigeminal ganglia
Latency
Spontaneous reactivation
Онлайн доступ:http://link.springer.com/article/10.1186/s12985-020-01344-8
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