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Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation.

Herpesvirus persistence requires a dynamic balance between latent and lytic cycle gene expression, but how this balance is maintained remains enigmatic. We have previously shown that the Kaposi's Sarcoma-Associated Herpesvirus (KSHV) major latency transcripts encoding LANA, vCyclin, vFLIP, v-miRNAs,...

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Principais autores: Hyojeung Kang, Andreas Wiedmer, Yan Yuan, Erle Robertson, Paul M Lieberman
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2011-08-01
Serija:PLoS Pathogens
Online dostop:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002140&type=printable
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