Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases

ABSTRACT Phenol-soluble modulins (PSMs) are the primary proteinaceous component of Staphylococcus aureus biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can lead to persistent infections such as those caused...

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Detalhes bibliográficos

Principais autores:	Matthew K. Howard, Karlie R. Miller, Brian S. Sohn, Jeremy J. Ryan, Andy Xu, Meredith E. Jackrel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2023-08-01
coleção:	mBio
Assuntos:	biofilm phenol-soluble modulins MRSA disaggregase amyloid
Acesso em linha:	https://journals.asm.org/doi/10.1128/mbio.00587-23
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