Reversal of Alpha-Synuclein Fibrillization by Protein Disulfide Isomerase
Aggregates of α-synuclein contribute to the etiology of Parkinson’s Disease. Protein disulfide isomerase (PDI), a chaperone and oxidoreductase, blocks the aggregation of α-synuclein. An S-nitrosylated form of PDI that cannot function as a chaperone is associated with elevated levels of aggregated α-...
Na minha lista:
| Principais autores: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020-07-01
|
| coleção: | Frontiers in Cell and Developmental Biology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/article/10.3389/fcell.2020.00726/full |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|