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Toxin Instability and Its Role in Toxin Translocation from the Endoplasmic Reticulum to the Cytosol

AB toxins enter a host cell by receptor-mediated endocytosis. The catalytic A chain then crosses the endosome or endoplasmic reticulum (ER) membrane to reach its cytosolic target. Dissociation of the A chain from the cell-binding B chain occurs before or during translocation to the cytosol, and only...

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Gorde:
Egile nagusia: Ken Teter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2013-12-01
Saila:Biomolecules
Gaiak:
AB toxin
cholera toxin
cytolethal distending toxin
endoplasmic reticulum-associated degradation
exotoxin A
pertussis toxin
ricin toxin
Shiga toxin
toxin structure
ubiquitin-independent degradation
Sarrera elektronikoa:http://www.mdpi.com/2218-273X/3/4/997
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